Figure 1

1. Figure 1 Eligible GPs Eligible GPs Questionnaire Questionnaire on on Participation Participation No 902 No 902 1194 1194 screening screening attitudes attitudes in trial in trial 292 292 700 700 Sampling Sampling 130 130 Sampling Sampling of target of target Sampling Sampling of of tqarget target 64 64 65 65 GP GP Randomization Randomization population population population population Guaiaco vs. Guaiaco vs. Immuno Immuno . . 2/10 = 3604 2/10 = 3604 2/10 = 3716 2/10 = 3716 1 withdrawal 1 withdrawal Individual randomiz Individual randomiz . . Individual randomiz Individual randomiz . . GP vs. hospital GP vs. hospital GP vs. hospital GP vs. hospital Guaiaco Guaiaco Immuno Immuno Immuno Immuno Guaiaco Guaiaco Hospital Hospital Hospital Hospital GP GP GP GP extreme extreme extreme extreme extreme extreme extreme extreme GPs GPs 65 65 GPs GPs 64 64 GPs GPs 64 64 GPs GPs 65 65 GPs GPs 27# 27# GPs GPs 9§ 9§ GPs GPs 15# 15# GPs GPs 9* 9* Pop. 1797 Pop. 1797 Pop. 1858 Pop. 1858 Pop. 1858 Pop. 1858 Pop. 1807 Pop. 1807 Pop. 666 Pop. 666 Pop. 238 Pop. 238 Pop. 522 Pop. 522 Pop. 238 Pop. 238 FOBT FOBT FOBT FOBT FOBT FOBT FOBT FOBT FOBT FOBT FOBT FOBT FOBT FOBT Not Returning Not Returning Returned Returned Not Returned Not Returned Returned Returned Not Returned Not Returned Returned Returned Not Returned Not Returned Returned Returned FOBT FOBT N 232 N 232 N 899 N 899 N 732 N 732 N 837 N 837 N 305 N 305 N 1031 N 1031 N 809 N 809 N 811 N 811 Sampling Sampling Sampling Sampling Sampling Sampling Sampling Sampling Sampling Sampling Sampling Sampling Sampling Sampling Sampling Sampling of of controls controls of of cases cases of of controls controls of of cases cases of of controls controls of of cases cases of of controls controls of of cases cases 120 120 125 125 164 164 155 155 123 123 133 133 149 149 145 145 * 1 <20% and 8 >80% * 1 <20% and 8 >80% § 7 <20% and 3 >80% § 7 <20% and 3 >80% # 15 <10% # 15 <10% # 27 <10% # 27 <10%