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This study investigates the differential expression of Egr-1 and Tubulin in various genotypes, including wild-type (WT) and knockout (KO) models, under diverse conditions. Using time points such as 1 hour and 2 hours, we explore the signaling pathways impacted by eIF2α phosphorylation. Our findings emphasize the dynamic interactions between these proteins in the cellular response, enhancing our understanding of their roles in cellular signaling and function.
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UT TG 1hr TG 2hr WT KO KO WT KO WT Egr-1 Tubulin
KO WT Tg 1hr WT Tg 1hr WT Tg 1hr KO Tg 1hr KO UT UT UT UT UT UT UT UT Egr-1 Tubulin KO WT UT 1 KO UT 2 KO UT 1WT UT 2WT TG 1 TG 1 TG 1 TG 1 TG 1 TG 1 TG 1 TG 1 Egr-1 Tubulin KO WT UT 3 WT UT 4 WT UT 3 KO UT 4 KO TG 2 TG 2 TG 2 TG 2 TG 2 TG 2 TG 2 TG 2 Egr-1 Tubulin
UT TG 1hr TG 2hr WT KO KO WT KO WT eIF2a[P] eIF2a