ELM PHOSPHO.ELM. June 2009 bioinformatics workshop. Irit Kisslov Noam Harif. E ukaryotic L inear M otif. Collection of small functional sites/motives. Examples: - protein interaction sites - cell compartment targeting signals - post-translational modifications sites
June 2009 bioinformatics workshop
Irit Kisslov Noam Harif
- protein interaction sites
- cell compartment targeting signals
- post-translational modifications sites
- cleavage sites
Difficult to analyse productively
There are many of them.
They are short.
No defined structure.
False positive results.
Building algorithm for prediction using ELM database.
Searching for the known motifs in given protein.
Evaluation of the results found by ELM.