Outline. Framework of ecotoxicology. Exposure, fate, and transportBioaccumulationToxicityBioaccumulation: uptake - excretion. Bioaccumulation. Accumulation from all sourcesWater, air, solidBioconcentration: from water only. Why study bioaccumulation?. Minamata Bay, Japan. 1956. Hg pollution. Landmark for environmental studies.DDT pesticides. egg shell thinningTBT, oyster shell thickness, imposex in snailsWithout the environments, we cannot even survive!.