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Pharmaceutical Dosage Forms . By S.Bohlooli, PhD School of Medicine, Ardabil University of Medical Sciences. Oral Tablets Capsules Solutions Syrups Elixirs Suspensions Magmas Gels Powders. Sublingual Tablets Troches and Lozenges Parenteral Solutions Suspensions Conjunctival
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Pharmaceutical Dosage Forms By S.Bohlooli, PhD School of Medicine, Ardabil University of Medical Sciences
Oral Tablets Capsules Solutions Syrups Elixirs Suspensions Magmas Gels Powders Sublingual Tablets Troches and Lozenges Parenteral Solutions Suspensions Conjunctival Contact lens inserts Ointments Dosage Form/ Drug Delivery System by route of administration
Epicutaneous / transdermal Ointments Creams Infusion pumps Pastes Plasters Powders Aerosols Lotions Transdermal patches, discs, solutions Intraocular/ intraaural Solutions Suspensions Intranasal Solutions Sprays Inhalers Ointments Intrarespiratory Aerosols Dosage Form/ Drug Delivery System by route of administration
Vaginal Solutions Ointments Emulsion foams Gels Tablets Inserts, suppositories, sponges Rectal Solutions Ointments Suppositories Urethral Solutions suppositories Dosage Form/ Drug Delivery System by route of administration
Solid Dosage Forms Powders and Granules Capsules and Tablets
Powders and Granules • Powders • Blending Powders • Medicated Powders • Aerosolized Powders • Granules • Effervescent
Capsules • Hard Gelatin Capsules • Soft Gelatin Capsules
Compressed tablets (C.T.) Multiple Compressed tablets (M.C.T.) Sugar-Coated Tablets (S.C.T.) Film Coated Tablets (F.C.T) Gelatin Coated Tablets Enteric Coated Tablets (E.C.T.) Buccal or Sublingual Tablets Chewable Tablets Effervescent Tablets Molded Tablets Immediate release Tablets (I.R.) Instant Disintegrating /Dissolving Tablets Extended release Tablets (E.R.) Vaginal Tablets Tablets
Compressed Tablets contains: • Medicinal agent • Diluents or filler • Binders or adhesives • Disintergrants • Lubricants • Miscellaneous adjuncts • Colorants and flavorants
Tablets Sugar-Coated Tablets Film Coated Tablets Multiple Compressed tablets Compressed tablets Enteric Coated Tablets Gelatin Coated Tablets
Modified Release Extended Release Delayed Release Repeat action Targeted Release Terminology of extended release Sustained Release (SR) Sustained Action (SA) Prolonged Action (PA) Controlled Release (CR) Extended Release (ER) Timed Release (TR) Long Acting (LA) Modified-Release Dosage Forms and Drug Delivery Systems
Modified-Release Dosage Forms Extended Release
Nonoral Modified-Release Systems • Ocular • Parenteral Systems • Vaginal Inserts • Subdermal Implants
Semi-Solid Dosage Forms Ointments Creams Gels Pastes Plasters
Pharmaceutical Inserts Suppositories Inserts
Liquid Dosage forms Solutions Disperse systems
Solutions • Oral Solutions • Otic Solutions • Ophthalmic Solutions • Topical Solutions • Spirits
Oral Liquid Dosage Forms • Oral solutions • Syrups • Elixirs • Tinctures
Example of Syrup • Antihistamine Syrup • Chlorpheniramine maleate 0.4g • Glycerin 25.0ml • Syrup base 83.0 ml • Sorbitol solution 283 ml • Sodium Bezoate 1.0 g • Alcohol 60.0 ml • Color and Flavor q.s. • Purified water to make 1000.0ml
Example of Elixir • Theophylline Elixir • Theophylline 5.3 g • Citric acid 10.0 g • Liquid Glucose 44.0 g • Syrup 132 ml • Glycerin 50.0 ml • Sorbitol Solution 324.0 ml • Alcohol 200.0 ml • Saccharin Sodium 50 g • Lemon Oil 0.5 g • FDC Yellow No. 5 0.1 g • Purified water to make 1000.0 ml
Disperse Systems • Suspensions • Emulsions • Aerosols
Sterile Dosage Forms and Delivery Systems Parenterals Biologicals Ophthalmic solutions and suspensions
Automatic injection Medi-Jector:Needle Free
Novel and Advanced Dosage Forms, Delivery Systems, and Devices Iontophoresis Phonophoresis Intravenous controllers and infusion pumps, lyposomes