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Analytical Ultracentrifugation

Analytical Ultracentrifugation. Density Gradient formed from various solutes:. ‘40s. ‘50s. RAFT MODEL. Current day. ‘70s. The hydrophobic effect:. Transfer from water to alcohol. MLVs. unilamellar vesicles. SUVs. Multilamellar vesicles. Liposomes as Membrane Mimetics. 50nm. 500nm.

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Analytical Ultracentrifugation

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  1. Analytical Ultracentrifugation Density Gradient formed from various solutes:

  2. ‘40s ‘50s RAFT MODEL Current day ‘70s

  3. The hydrophobic effect: Transfer from water to alcohol

  4. MLVs unilamellar vesicles SUVs Multilamellar vesicles

  5. Liposomes as Membrane Mimetics 50nm 500nm 5000nm As vesicles get smaller, they tumble more quickly, have a higher surface curvature, less interior volume, are less thermodynamically stable, and less symmetry in lipid distribution

  6. Freeze-fracture electron microscopy

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