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Decoding Gene Linkage and Chromosomes: Understanding Inheritance Patterns

Delve into the Chromosomal Theory of Inheritance linking genes to chromosomes. Explore how genes map to specific locations, the role of meiosis, random assortment, and gene linkage through related distances. Discover the inheritance nuances based on Thomas Morgan Hunt's research using fruit flies.

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Decoding Gene Linkage and Chromosomes: Understanding Inheritance Patterns

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  1. KEY CONCEPT Genes can be mapped to specific locations on chromosomes.

  2. Chromosomal Theory of Inheritance-based on research of Thomas Morgan Hunt • Genes are located on chromosomes and the behavior of chromosomes during meiosis accounts for inheritance patterns. “Random Assortment” • Chromosomes exchange homologous genes during meiosis explains how linked genes can separate.

  3. Linkage maps estimate distances between genes and show the relative locations of genes. Gene Linkage -the closer together two genes are, the more likely they will be inherited together. Linkage Maps –indicatethe related to distances between genes by examining the cross-over frequencies.

  4. Cross-over frequencies can be converted into map units. • gene A and gene B cross over 6.0 percent of the time • gene B and gene C cross over 12.5 percent of the time • gene A and gene C cross over 18.5 percent of the time

  5. Mutant Wild type Gene linkage was explained through fruit flies. Linked genes are not inherited together every time.

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