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Epidemiology. The incidence of appendectomy appears to be declining due to more accurate preoperative diagnosis.Despite newer imaging techniques, acute appendicitis can be very difficult to diagnose. . Pathophysiology. Acute appendicitis is thought to begin with obstruction of the lumenObstruction can result from food matter, adhesions, or lymphoid hyperplasiaMucosal secretions continue to increase intraluminal pressure.

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