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Traditional Inheritance. Mendelian inheritanceDiseasesSingle gene defects/disordersAutosomal inheritanceDominant e.g. Marfan\'s syndromeRecessive e.g. Thalassaemia majorX-linked recessive e.g. Haemophilia. Non-traditional Inheritance. Polygenic or multifactorial inheritanceE.g. Diabetes mellitusMitochondrial inheritanceE.g. Sensorineural hearing lossGenomic imprinting and uniparental disomyE.g. Prader-Willi SyndromeTrinucleotide repeat expansionE.g. Fragile X syndrome.

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