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World. tubal ligation 32%. vasectomy 7%. IUD 22%. condom 7%. CI/PA 13%. oral contraceptives 14%. D/P/S 5%. Germany. IUD 8%. tubal ligation 1%. oral contraceptives 77%. vasectomy 2%. condom 6%. CI/PA 4%. Nieschlag & Behre Andrology 2nd ed.
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World tubal ligation 32% vasectomy 7% IUD 22% condom 7% CI/PA 13% oral contraceptives 14% D/P/S 5% Germany IUD 8% tubal ligation 1% oral contraceptives 77% vasectomy 2% condom 6% CI/PA 4% Nieschlag & Behre Andrology 2nd ed. Springer 2000 D/P/S 2% EN-F1620E
Approaches to male contraception Methods in use Vasectomy Vas occlusion Condom Coitus interruptus Physical approach Ultrasound Temperature Immunological Immun. against sperm approach antigens (e.g. p34h) Pharmacological Chlorinated sugars approach Nitroimidazole derivatives Sulfasalazine Gossypol Tripterigium wilfordii Hormones Nieschlag & Behre Andrology 2nd ed. Springer 2000 EN-F1529E
Approaches to hormonal male contraception Nieschlag 2002 1. Inhibition of FSH 2. Testosterone (T) alone 3. T + gestagens 4. T + estrogens 5. T + 5a-reductase inhibitors 6. T + GnRH agonists 7. T + GnRH antagonists EN-F1530b
The Weimar Manifesto on Male Contraception June 29, 1997 “... The researchers agreed that clinical research had shown that a reversible male hormonal contraceptive is feasible and effective ...” “... Since any contraceptive method can only be brought to practical usage by pharmaceutical com-panies, the researchers urged the pharmaceutical industry to become actively involved in the develop-ment of novel male contraceptives...” EN-F1519E (From Nieschlag & Behre, Testosterone, 2nd ed. Springer 1998)
