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Case Study: Amnesia

Case Study: Amnesia. anterograde and retrograde amnesia in a person with bilateral fornix lesions following removal of a colloid cyst. AD’s Story. 45-year-old male no reports of memory loss complained about severe headaches discovery of cyst surgery without complication woke up confused.

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Case Study: Amnesia

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  1. Case Study: Amnesia anterograde and retrograde amnesia in a person with bilateral fornix lesions following removal of a colloid cyst

  2. AD’s Story • 45-year-old male • no reports of memory loss • complained about severe headaches • discovery of cyst • surgery without complication • woke up confused

  3. Lesions • bilateral fornix • small spot on basal forebrain • no damage to hippocampus • localized and generally small

  4. Amnesia • anterograde: LTM not STM • retrograde: • lifelong autobiographical episodic memory • personal semantic memory partially impaired

  5. Dissociation • remote episodic and semantic memory • recollection of episodic memories • recovery of semantic memories • the role of context

  6. Testing • WAIS-R: high in average range • WMS-R story recall: • immediate: impaired • delayed: what test? • AMI: • episodic severely impaired • semantic slightly impaired

  7. Research • anterograde: consistent with past studies • retrograde: • confirms selective contribution • new evidence for dissociation • contradicts claim regarding lateral neocortex

  8. Outlook & Critique • some minimal improvement (3 to 9 mo.) • contribution of basal forebrain lesion? • lesions avoidable?

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