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Protein Function

Protein Function. Protoporphyrin. Heme. Spacefill representation of heme. Iron in Mb-bound heme can not be oxidized. Myoglobin. Ligand binding to heme. Mb increases the selectivity of O 2 binding. Ligand binding equilibrium. O 2 binding by Mb. Hb subunits are homologous to Mb.

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Protein Function

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  1. Protein Function

  2. Protoporphyrin

  3. Heme

  4. Spacefill representation of heme

  5. Iron in Mb-bound heme can not be oxidized

  6. Myoglobin

  7. Ligand binding to heme

  8. Mb increases the selectivity of O2 binding

  9. Ligand binding equilibrium

  10. O2 binding by Mb

  11. Hb subunits are homologous to Mb

  12. Dominant interactions in Hb tetramer

  13. T-Hb: stabilizing interactions

  14. T-Hb: more stabilizing interactions

  15. Going from T to R

  16. Going from T to R

  17. Going from T to R: functional consequences

  18. The Hill coefficient

  19. Effect of pH on O2 binding

  20. Effect of pH on O2 binding

  21. The CO2 transport

  22. Binding of CO2 stabilizes T-Hb

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