Welcome to Bio 290, Introduction to Genetics!. Today’s Agenda:. Introduction of Colleagues Introduction to Course, Expectations, and Website Reviewing the Foundations of Genetics (In-Class Assignment 1) Introduction to Single-Gene Inheritance (Ch 2) Poster Project Brainstorm.
3. Mendel’s Contributions
Watch for some new terms here! What does it mean to be haplosufficient, or haploinsufficient? What’s a leaky mutation?
4. Chromosome Structure and Function During Meiosis
FIGURE: Model of the synaptonemal complex (SC). Lateral elements (light blue rods) of homologous chromosomes align and synapse together via a meshwork of transverse filaments (white lines) and longitudinal filaments (dark blue rods). The longitudinal filaments are collectively referred to as the "central element" of the SC. Ellipsoidal structures called recombination nodules (e.g., gray ellipsoid) are constructed on the central region of the SC. (Image: Mississippi Genome Exploration Lab)
5. Value and Diversity of Model Organisms
What advantages do Drosophila, above, provide for a geneticist?
What advantage might a haploid-dominant organism like yeast, above, provide for a geneticist?
What advantages do mice as a model organism offer a geneticist? Any disadvantages?
6. Sex-Liked Genes Have Unusual Inheritance Patterns
What’s unusual about white-eyed fruit flies?
Watch for new terms: What does it mean to be hemizygous? What’s a? pseudoautosomal region
7. Pedigree Analysis is a Powerful Way to Represent Inheritance
What are the most interesting recent developments in Genetics? What do I find fascinating about the field?