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Interactive Deformable Registration with Landmarks: Advances in Radiation Oncology Imaging

This meeting discusses the innovative use of interactive deformable registration with landmarks in radiation oncology. It focuses on various techniques, including Radial Basis Functions, Wendland, and Gaussian methods for managing global and local support. The applications highlighted span significant clinical issues, such as capturing local image details, addressing anatomic changes, and accommodating variations stemming from tumor shrinkage, weight loss, or body movements. Join us to explore these advanced methodologies for improved precision in treatments, especially in light of significant volumetric changes.

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Interactive Deformable Registration with Landmarks: Advances in Radiation Oncology Imaging

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  1. 3D Slicer Users Group Meeting Nadya Shusharina Department of Radiation Oncology Massachusetts General Hospital AAPM/COMP Vancouver, August 2, 2011

  2. Interactive deformable registration with landmarks Radial Basis Functions • TPS (global support) • Wendland (local support) • Gaussian (global support with variable kernel width, allowed for local regularization)

  3. Areas of application • local details of the image, primarily the details of low contrast • anatomic changes • tumor shrinking • weight loss • gross body movement • breathing • position variation • substantial volume change • full vs empty bladder or rectum

  4. Misalignment caused by anatomic changes

  5. Misalignment caused by position variation

  6. Misalignment caused by position variation

  7. Misalignment caused by the rectum enlargement

  8. To learn more http://www.slicer.org/slicerWiki/index.php/Modules:PlastimatchLANDWARP

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