patient d c laparoscopic renal cryoablation n.
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Patient D.C. Laparoscopic Renal Cryoablation - PowerPoint PPT Presentation


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Patient D.C. Laparoscopic Renal Cryoablation. Indications. Renal tumors < 4cm Peripheral or Exophytic Separate from the collecting system Bilateral synchronous tumors Solitary kidney or compromised renal function. Mechanism of Tissue Injury. Immediate Direct effect of freezing the cells

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indications
Indications
  • Renal tumors < 4cm
  • Peripheral or Exophytic
  • Separate from the collecting system
  • Bilateral synchronous tumors
  • Solitary kidney or compromised renal function
mechanism of tissue injury
Mechanism of Tissue Injury
  • Immediate
    • Direct effect of freezing the cells
  • Delayed
    • vascular insufficiency and destruction of tissue
    • coagulative necrosis
freezing
Freezing
  • Ice forms in the extracellular compartment
  • This draws fluid out of the cell causing chemical damage to the cell
  • Crystals form in the intracellular space
thawing
Thawing
  • Re-crystallization & fusion of smaller crystals (severe damage)
  • Vasoconstriction & halt in circulation during freeze
    • porous endothelium
    • edema
    • platelet aggregation
    • thrombosis and ischemia