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BLOOD

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  1. BLOOD

  2. FUNCTION • TRANSPORT NUTRIENTS, WASTES, GASES • REGULATE FLUID AND ELECTROLYTE, ACID-BASE, AND BODY TEMPERATURE • PROTECT AGAINST PATHOGENS

  3. CHARACTERISTICS OF BLOOD • AMOUNT • COLOR • pH • VISCOSITY

  4. CONTENTS OF BLOOD • PLASMA • LIQUID PORTION, APPROX 91% IS WATER • BLOOD CELLS INCLUDING 1. RBC 2. WBC 3. PLATELETS

  5. BLOOD CELL PRODUCTION • PRODUCED IN HEMOPOIETIC TISSUES (RED BONE MARROW) AND LYMPHATIC TISSUE (SPLEEN, LYMPH NODES) • BONE MARROW CONTAINS STEM CELLS (PRECURSOR CELLS)

  6. STEM CELLS • VITAMIN B12 AND FOLIC ACID ARE NECESSARY FOR DNA SYNTHESIS IN THE STEM CELLS

  7. RBC AKA ERYTHROCYTES • BICONCAVE, CIRCULAR • MATURE RBC HAVE NO NUCLEI • FUNCTIONS IS TO CARRY OXYGEN ON THE HEMOGLOBIN (Hgb) • IRON IS ESSENTIAL IN THE FORMATION OF Hgb

  8. RBC AKA ERYTHROCYTES DID YOU KNOW… THE BODY MAKES SEVERAL MILLION NEW RBC/SECOND RBC’s LIVE APPROX 120 DAYS

  9. RBC DEATH • THE IRON PORTION IS REABSORBED AND STORED BY THE LIVER • THE HEME PORTION IS A WASTE PRODUCT

  10. BLOOD TYPES • O, A, B, AB • O IS UNIVERSAL DONOR • AB IS UNIVERSAL RECIPIENT • IF GIVEN THE WRONG BLOOD TYPE, AGGLUTINATION AND HEMOLYSIS OCCURS

  11. Rh FACTOR • AN ANTIGEN PRESENT IN THE BLOOD • ERYTHROBLASTOSIS FETALIS

  12. WBC AKA LEUKOCYTES • FUNCTION IS TO PROTECT THE BODY FROM INFECTION AND TO PROVIDE IMMUNITY • LARGE THAN RBC AND CONTAIN A NUCLEUS

  13. 5 TYPES OF WBC • EOSINOPHILS – DETOXIFY FOREIGN PROTEINS • BASOPHILS – CONTAIN HEPARIN AND HISTAMINE • NEUTROPHILS AND MONOCYTES – PHAGOCYTIZE PATHOGENS • LYMPHOCYTES PRODUCE ANTIBODIES

  14. PLATELETS AKA THROMBOCYTES • HEMOSTASIS (PREVENTION OF BLOOD LOSS) • PROVIDES CLOTTING BY 1. VASCULAR SPASM (FOR LARGE VESSELS) 2. PLATELET PLUG (FOR CAPILLARY RUPTURE) 3. CHEMICAL CLOTTING – CLOT FORMS IN A SERIES OF STEPS

  15. TERMS • THROMBUS – CLOT • EMBOLISM – A MOVING CLOT