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Analysis of Retroviral Elements in Human Tissues: DNA Stability and Control Mechanisms

This study investigates the presence and behavior of endogenous retroviral elements (ERVs) in human kidney, lung, and liver tissues. Using a 100 bp ladder for DNA fragment analysis across multiple control settings over periods ranging from 3 to 24 hours, we explore the genetic stability of retroviral constructs and their relationship with cellular integrity. Observations on burn treatment effects on DNA samples reveal insights into the thermal resilience of these elements, contributing to our understanding of their role in human health and disease.

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Analysis of Retroviral Elements in Human Tissues: DNA Stability and Control Mechanisms

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  1. ERV U2 5’ LTR 3’ LTR A env pol gag R R U3 U5 U3 U5 ERV U1 Kidney Lung Liver B control 3 hours 3 hours 3 hours 24 hours control 24 hours control 24 hours 100 bp ladder 100 bp ladder 100 bp ladder 100 bp ladder 100 bp ladder 100 bp ladder DNA DNA DNA no burn no burn no burn burn no burn burn burn no burn burn burn no burn burn 1,500 bp 600 bp

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