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Monday, March 12, 2012 , 6 pm s.t. Seminar Room Hans Borst Centre in the building I11 , MHH,

Cluster of Excellence - “From Regenerative Biology to Reconstructive Therapy”. Special Lecture:.

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Monday, March 12, 2012 , 6 pm s.t. Seminar Room Hans Borst Centre in the building I11 , MHH,

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  1. Cluster of Excellence - “From Regenerative Biology to Reconstructive Therapy” Special Lecture: Noriyuki Kasahara, MD PhDProfessor, Departments of Medicine and Molecular & Medical PharmacologyDirector, JCCC Vector Shared Resource & CURE Vector Core FacilityUniversity of California, Los Angeles (UCLA)President, International Society for Cell & Gene Therapy of Cancer (ISCGT)UCLA David Geffen School of Medicine“Translational development of novel therapies at the interface of cancer, transplantation, and regenerative medicine:  Light at the end of the tunnel?” Monday, March 12, 2012 , 6 pm s.t. Seminar Room Hans Borst Centre in the building I11, MHH, Carl-Neuberg-Str 1, 30625 Hannover Contact: Prof. Renata Stripecke Tel. 0511 / 532-6999

  2. Cluster of Excellence - “From Regenerative Biology to Reconstructive Therapy” Special Lecture: Noriyuki Kasahara, MD PhDAbstract:The use of tumor-selectively replicating viruses for tumor mass reduction and destruction of its immunosuppressive milieu, combined with the use of more potent genetically-engineered cancer vaccines and immune effector cells, may provide a new generation of biological therapies, which are now being tested in clinical trials.  Conversely, immunosuppressive mechanisms evolved by tumors may provide useful clues for genetic engineering of allograft cells to avoid immune rejection.  Furthermore, the ability to genetically engineer stem cells has opened new possibilities for the development of novel therapies for cancer, transplantation, and regenerative medicine.  This lecture will focus on the interface between these areas of research, and current strategies that are reaching the stage of clinical translation.

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