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GEMSS : G rid- E nabled M edical S imulation S ervices. Healthgrid Cluster Meeting Project Overview: Profile from CORDIS Consortium Project Goals / Objectives GEMSS System Design Medical Applications Clustering IST-2001-37153. GEMSS Project Profile (Cordis).

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gemss g rid e nabled m edical s imulation s ervices
GEMSS: Grid-Enabled Medical Simulation Services

Healthgrid Cluster Meeting

Project Overview:

Profile from CORDIS

Consortium

Project Goals / Objectives

GEMSS System Design

Medical Applications

Clustering

IST-2001-37153

slide2

GEMSS Project Profile (Cordis)

Project Acronym: GEMSS

Title: GRID-enabled Medical Simul. Services

Subject Index :Policies; Legislation, Regulations;Information Processing,

Information Systems; Electronics, Microelectronics

Start Date:2002-09-01End Date:2005-02-28Duration:30 Ms

Project Status: Accepted

Project Cost: 3.59 million € Funding: 2.63 million €

Programme Type: 5th FWP (Fifth Framework Programme)

Programme Acronym : IST

Subprogramme Area: Cross Programme Actions (CPA) –

CPA9: Grid test beds, deployment and technologies

Project Reference: IST-2001-37153

Contract Type: CSC (Cost-sharing contracts)

gemss consortium

No

Partner Role

Country

Specific Expertise

1

NEC C

C&C R.L.

UK (Germany)

2

MPI P

Germany

3

ISS P

Austria

4

USFD P

STH S

UK

5

AEA P

UK

6

IT- P

Innovation

UK

7

CRID P

Belgium

Grid Software /solutions

Bio-numeric modelling

Simulation/Imaging SW

Medical Expertise

Legal Aspects

8

ASD A

Germany

9

IDAC A

Ireland

10

IBMTP A

Austria

GEMSS Consortium

Legend: C – Co-ordinator P – Principal Contractor S – Subcontractor A – Associate Contractor

slide4

The main goals of GEMSS are :

  • Install an extendible, interoperable and collaborative testbed for GRID-enabled medical application services,
  • Demonstrate the medical significance of the GEMSS models,
  • Demonstrate the functionality of the GRID-infrastructure,
  • Open a business model for future commercial exploitation.
slide5

Simulation portal

A general overview / possible scenario

Medical simulation service Portal + networked compute resources

User-site

(SW installed)

Simulation Service System

GRID SW (interface)

GRID

SW

Pre- & Post-

processing

Applications SW

GRID SW (service use)

Internet

or Intranet

Could also be moved

to the services portal

slide6

GEMSS Project Objectives

GEMSS will demonstrate that the Grid can be used to provide medical practitioners and researchers with access to advanced simulation and image processing services for improved pre-operative planning and near real-time surgical support.

The GEMSS will build on top of existing Grid technologies, maintaining compliance with standards thereby ensuring future extensibility and interoperability, to provide support for authorisation, workflow, security, error detection and recovery.

Test-bed to evaluate & validate the GEMSS environment, including its integration into the end-users working environments.

GEMSS aims to anticipate privacy, security and other legal concerns by examining and incorporating into its Grid services the latest laws and EU regulations related to providing medical services over the Internet.

slide7

GEMSS System Design

Generic GRID-services:

build on existing GRID and WEB technologies

like OGSA, Web services, Jini and Corba,

service interaction models, protocols & interfaces,

QoS (time critical services),

security models compliant with European legal issues,

fail-over and recovery from errors,

workflow and service orchestration techniques for time-critical processes,

medical GRID portals, PSEs, application servers.

Medical service applications:

Numerical modelling, based on existing software

packages such as CFX and EASA,

High Performance Computing (HPC) simulation, FE analysis,

Advanced image processing.

Collaborative tools:

tele-support,

tele-consulting.

slide8

Grid Architecture

Application

Layer

Collective

Layer

Resource

Layer

Fabric

Layer

Applications, Portals, Environments

Higher Services, APIs, Protocols

APIs, Protocols, SDKs

Computers, Networks, Devices

slide9

Grid Architecture

Application

Layer

Collective

Layer

Resource

Layer

Fabric

Layer

Applications, Portals, Environments

Higher Services, APIs, Protocols

Globus toolkit

APIs, Protocols, SDKs

Computers, Networks, Devices

slide10

Condor

Grid Architecture

Application

Layer

Collective

Layer

Resource

Layer

Fabric

Layer

Applications, Portals, Environments

Higher Services, APIs, Protocols

APIs, Protocols, SDKs

Computers, Networks, Devices

slide11

Legion

Grid Architecture

Application

Layer

Collective

Layer

Resource

Layer

Fabric

Layer

Applications, Portals, Environments

Higher Services, APIs, Protocols

APIs, Protocols, SDKs

Computers, Networks, Devices

slide12

UNICORE

Grid Architecture

Application

Layer

Collective

Layer

Resource

Layer

Fabric

Layer

Applications, Portals, Environments

Higher Services, APIs, Protocols

APIs, Protocols, SDKs

Computers, Networks, Devices

slide13

UNICORE

Legion

Condor

Grid Architecture

Application

Layer

Collective

Layer

Resource

Layer

Fabric

Layer

Applications, Portals, Environments

Higher Services, APIs, Protocols

Globus toolkit

APIs, Protocols, SDKs

Computers, Networks, Devices

Which one to use?

slide14

GEMSS: Medical Applications

Maxillo-facial Surgery Simulation

During maxillo-facial surgery a steel device is tightly fixed to the head by special screws. These screws deform the skull which becomes clearly visible as a result of a parallel finite element analysis. The goal is to provide a virtual planning space for the optimisation the fixation and distraction procedures.

Partners: NEC MPI

Test-bed Applications

(1) Maxillo-facial surgery simulation.

(2) Neuro-surgery support.

(3) Radio-surgery simulation.

(4) Inhaled drug-delivery simulation.

(5) Cardio-vascular system simulation.

(6) Advanced image reconstruction.

Phase I:

Halo positioning

Phase II:

Distraction Procedure

slide15

GEMSS: Medical Applications

Neuro Surgery Support

Prediction of the brain shift during neurosurgery is important to provide co-ordinates for the surgical navigation. In GEMSS a robust and precise approach based on non-linear image registration will be implemented in a Grid environment.

Partner(s): MPI

Test-bed Applications

(1) Maxillo-facial surgery simulation.

(2) Neuro-surgery support.

(3) Radio-surgery simulation.

(4) Inhaled drug-delivery simulation.

(5) Cardio-vascular system simulation.

(6) Advanced image reconstruction.

slide16

GEMSS: Medical Applications

Radio-surgery simulation

Revised treatment plan simulated

- different beam weighting and orientation

RAPT simulation now shows better coverage

- differs from conventional treatment analysis

New treatment more likely to be successful.

Partner(s): IT-Innovation, USFD

Test-bed Applications

(1) Maxillo-facial surgery simulation.

(2) Neuro-surgery support.

(3) Radio-surgery simulation.

(4) Inhaled drug-delivery simulation.

(5) Cardio-vascular system simulation.

(6) Advanced image reconstruction.

slide17

GEMSS: Medical Applications

Inhaled Drug-Delivery Simulation

Take-up of the Cophit project –

A combination of computational fluid dynamics and 1-dimensional models to optimise delivery of inhaled drugs to the lung.

Partner(s): USFD, AEA, ASD

Test-bed Applications

(1) Maxillo-facial surgery simulation.

(2) Neuro-surgery support.

(3) Radio-surgery simulation.

(4) Inhaled drug-delivery simulation.

(5) Cardio-vascular system simulation.

(6) Advanced image reconstruction.

slide18

GEMSS: Medical Applications

Cardio-vascular System Simulation

A compartmental approach and coupled structural mechanics and fluid dynamics will be applied to simulate the entire cardio-vascular system.

Partner(s): USFD, AEA, ASD, IDAC

Test-bed Applications

(1) Maxillo-facial surgery simulation.

(2) Neuro-surgery support.

(3) Radio-surgery simulation.

(4) Inhaled drug-delivery simulation.

(5) Cardio-vascular system simulation.

(6) Advanced image reconstruction.

Heart-valve example kindly provided by the BLOODSIM project.

slide19

Hospital A

Internet

...

Hospital Z

Reconstruction Service

GRID

Agent

...

Reconstruction Service

GEMSS: Medical Applications

Advanced Image Reconstruction

Entropy-based parallel Projection Image Reconstruction for SPECT.

The medical image reconstruction system is based on a service oriented architecture to provide clients with advanced fully 3D image reconstruction services running transparently on remote parallel computers.

Partner(s): ISS, IBMTP

Test-bed Applications

(1) Maxillo-facial surgery simulation.

(2) Neuro-surgery support.

(3) Radio-surgery simulation.

(4) Inhaled drug-delivery simulation.

(5) Cardio-vascular system simulation.

(6) Advanced image reconstruction.

slide20

Healthgrid Cluster Activities

  • GEMSS contributions:
  • Participation in the GGF.
  • Participation in GridStart.
  • Establish contact with related projects to identify common interests and synergies.
  • Consolidation of technical developments.
  • Identification of possible tool sharing.
  • Interoperability and standardisation efforts.
  • Common dissemination in health-related events.
suggestions for clustering
Suggestions for Clustering
  • CROSSGRID

As the first application, a Grid-based prototype system for pre-treatment planning in vascular interventional and surgical procedures will be developed through real-time interactive simulation of vascular structure and flow. The system consists of a distributed real-time simulation environment, in which a user interacts in Virtual Reality (VR). A 3D model of the arteries, derived using medical imaging techniques, will serve as input to a real-time simulation environment for blood flow calculations. The user will be allowed to change the structure of the arteries, thus mimicking a surgical procedure and the effects of this adaptation will be analysed in real time while the results are presented to the user in a virtual environment.

suggestions for clustering1
Suggestions for Clustering
  • CROSSGRID + GEMSS

common interests:

Simulation/visualisation,

Medical LBA

(Lattice Boltzmann for scan data)

suggestions for clustering2
Suggestions for Clustering
  • EUROGRID (Bio/Meteo/CAE-GRID)
  • The objectives of the EUROGRID project are:
    • To establish a European GRID network of leading High Performance Computing centres from different European countries.
    • To operate and support the EUROGRID software infrastructure. The EUROGRID software will use the existing Internet network and will offer seamless and secure access for the EUROGRID users.
    • To develop important GRID software components and to integrate them into EUROGRID (fast file transfer, resource broker, interface for coupled applications and interactive access). 
    • To demonstrate distributed simulation codes from different application areas (Biomolecular simulations, Weather prediction, Coupled CAE simulations, Structural analysis, Real-time data processing).
    • To contribute to the international GRID development and to liase with the leading international GRID projects.
    • To productise the EUROGRID software components. After project end the EUROGRID software will be available as supported product.
suggestions for clustering3
Suggestions for Clustering
  • EUROGRID+ GEMSS

common interests:

UNICORE

Bio-GRID

HPC GRID

gemss contact info
GEMSS: Contact & Info

Contact: fingberg@ccrl-nece.de

Dr. Jochen Fingberg

C&C Research Laboratories

NEC Europe Ltd.

Tel. +49 2241 92520

Project site: http://www.gemss.de

Cordis: http://dbs.cordis.lu