Bedside Sensory Testing. A set of standardized procedures using standardized equipment to conduct basic sensory testing with minimum cost and patient burden ‘Kits’ have been developed and partially validated with procedures and equipment for osteoarthritis (OA) and post-herpetic neuralgia (PHN).
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OA subjects with dysfunctional DNIC showed greater discrimination of naproxen from placebo.
Consistent with Yarnitsky’s (2012) report that poor DNIC function predicted response to duloxetine in PHN.
OA subjects’ DNIC made no difference in open-label treatment with milnacipran (double-blind period showed no efficacy net vs. placebo either)