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Gully APC Burns, Jessica A Turner

Bottom -up curation of terminology for experimental variables: the Ontology of Experimental Variables and Values ( OoEVV ). Gully APC Burns, Jessica A Turner . Science is Cyclic. Cycles of Scientific Investigation ( ‘ CoSI ’ model).  ☐ ☐ ☐☐ ☐☐ ☐☐ ☐. Focus on Experimental V ariables.

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Gully APC Burns, Jessica A Turner

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  1. Bottom-up curation of terminology for experimental variables: the Ontology of Experimental Variables and Values (OoEVV) Gully APC Burns, Jessica A Turner

  2. Science is Cyclic Cycles of Scientific Investigation (‘CoSI’ model) ☐ ☐☐☐ ☐☐☐☐☐

  3. Focus on Experimental Variables ‘CDNF protects nigral dopaminergic neurons in-vivo’ This statistically-significant effect is the experimental basis for the findings of this study. from Lindholm, P. et al. (2007), Nature, 448(7149): p. 73-7 Cycles of Scientific Investigation (‘CoSI’ model) ☐☐☐☐ ☐☐☐☐☐

  4. Capturing Experimental Variables in Context http://www.bioscholar.org/ Knowledge Engineering from Experimental Design (KEfED) ☐☐ ☐ ☐☐☐☐☐

  5. Knowledge Engineering from Experimental Design (‘KEfED’) Khan et al. (2007), J. Neurosci. 27:7344-60 [expt 2] Knowledge Engineering from Experimental Design (KEfED) ☐☐ ☐ ☐☐☐☐☐

  6. OoEVV Basic Design Mathematical encoding of the variable Quality being measured (conceptual, no encoding) Variable measuring the quality 1 1 * * Scale Quality Variable ‘Handedness’ Simple-handedness-category [‘left’, ‘right’, ‘ambidextrous’] Edinburgh-handedness-score [ -100 … +100 ] Ontology of Variables and Values (OoEVV) ☐☐☐☐ ☐☐☐☐

  7. OoEVVImplementation Ontology of Variables and Values (OoEVV) ☐☐☐☐ ☐☐☐☐

  8. Measurement Scales Ontology of Variables and Values (OoEVV) ☐☐☐☐ ☐☐☐☐

  9. Software Development Ontology of Variables and Values (OoEVV) ☐☐☐☐ ☐☐☐☐

  10. OoEVVSoftware http://www.isi.edu/projects/ooevv/ooevv_software Ontology of Variables and Values (OoEVV) ☐☐☐☐ ☐☐☐☐

  11. OoEVV Viewer Ontology of Variables and Values (OoEVV) ☐☐☐☐ ☐☐☐☐

  12. Acknowledgements BMKEG@ISI Marcelo Tallis Drashti Dave Ed Hovy Biomedical Informatics Research Network (BIRN) Joe Ames Jose Luis Ambite Naveen Ashish Funding FBIRN: RR021992 BIRN: RR025736 CogPO: MH084812 BioScholar: GM083871 Thank you for listening!

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