1 / 13

Human Blood Groups- Multiple Alleles AND CoDominance

Human Blood Groups- Multiple Alleles AND CoDominance. OK… Humans and many other primates. Recall: There are three different alleles for human blood type (multiple alleles):.

jorn
Download Presentation

Human Blood Groups- Multiple Alleles AND CoDominance

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Human Blood Groups-Multiple Alleles AND CoDominance OK… Humans and many other primates

  2. Recall: There are three different alleles for human blood type (multiple alleles): • “A” indicates the presence of 1 type of antigen (protein that can “activate” your immune system) and “B” represents a different antigen on the surface of a red blood cell • “O” has no antigen on the surface of the RBC

  3. Antibodies • A “foreign” antigen will trigger your immune system to create antibodies. • Since antibodies are proteins, they have a specific shape & will attach onto the antigen for which they were made. • There are bacteria in the atmosphere that have a very similar shape to our “A” and “B” antigens & we are exposed to them as soon as we are born.

  4. Therefore, each person can have antibodies against an antigen they didn’t inherit. • These antibodies are floating around in our blood with our RBC’s.

  5. Type A blood (has A antigens on cell surface) has Anti-B antibodies • Antibodies are named for what they attack • Anti-B antibodies attack and will clump up (agglutinate) in the presence of B-antigen • Type B blood (has B antigens on cell surface) has A-antibodies

  6. Type AB blood doesn’t have any antibodies • Type O blood has Anti-A and Anti-B antibodies

  7. Rh Factor • The Rh factor genetic information is also inherited from our parents, but it is inherited independently of the ABO blood type alleles (a separate gene).

  8. There are 2 different alleles for the Rh factor known as Rh+ and Rh-. • Normal dominant/recessive inheritance • Positive (+) allele is dominant to negative (-) allele • Rh +: you have the protein Rh-: you don’t

  9. The “Rh Issue”… Mom = Rh- Baby #1 = Rh+

More Related