1 / 34

2. CODOMINANCE, INCOMPLETE DOMINANCE AND MULTIPLE ALLELES

2. CODOMINANCE, INCOMPLETE DOMINANCE AND MULTIPLE ALLELES. Compiled by Siti Sarah Jumali Level 3 Room 14 Ext 2123. Lecture outline . 2 nd Topic – extention of Mendelian Genetics Codominance Incomplete dominance Multiple alleles Lethal alleles Epistasis Polygenic inheritance

cate
Download Presentation

2. CODOMINANCE, INCOMPLETE DOMINANCE AND MULTIPLE ALLELES

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. 2. CODOMINANCE, INCOMPLETE DOMINANCE AND MULTIPLE ALLELES Compiled by Siti Sarah Jumali Level 3 Room 14 Ext 2123

  2. Lecture outline • 2nd Topic – extention of Mendelian Genetics • Codominance • Incomplete dominance • Multiple alleles • Lethal alleles • Epistasis • Polygenic inheritance • Linked genes • Crossover value and genes mapping • Sex linked genes

  3. TWO ALLELES

  4. CODOMINANCE • Co- means together codominant means equal in dominance • alleles are approximately equal effect in individuals; alleles are equally detectable in individuals. • Phenotypes for both alleles are exhibited in the heterozygote • The hybrid shows neither of the parents’ trait, instead, a third, different phenotype • Examples of this is blood types; ABO, iAiB.

  5. Pay attention on how to write codominance; Writing it is with superscript

  6. example

  7. Calico cat

  8. Unlike Law of Segregation.. • Using the calico cat as example, The genotype for fur can be represented as CB or CO. • CBis for black color and • CO denotes orange color • Therefore the codominance is written as • CBCBx COCO  100% CBCO

  9. Common situation of Codominance • Common phenotype used is roan fur in cattle • Cattle can either be all red RR; all white WW or; Roan RW

  10. Roan cattle

  11. Other example • Human blood type AB • Two types of protein A and B appear together on the surface of blood cells

  12. Question: • What is the probability of a child having type AB blood if one of the parents is heterozygous for A blood and the other is heterozygous for B blood? • What other genotypes are possible for children of these parents?

  13. INCOMPLETE DOMINANCE • A form of intermediate inheritance in which one allele for a specific trait is not completely dominant over the other allele. • The heterozygote has an intermediate phenotype between that of either homozygote • This results in a combined phenotype. Pink Snapdragon Rosendahl

  14. Example • In cross-pollination experiments between red and white snapdragon plants, the resulting offspring are pink. • The dominant allele that produces the red color is not completely expressed over the recessive allele that produces the white color. 

  15. Incomplete dominance eg • Crossing of organisms that has two different phenotypes produces offspring with another different phenotype which is a blend of the parental traits • Examples??????

  16. Snakes

  17. Test cross for Incomplete dominance

  18. Punnet Square for Incomplete dominance

  19. Try this • 1. Predict the phenotypic ratios ofoffspring when a homozygous white cow is crossed with a roan bull. • 2. What should the genotypes & phenotypes for parent cattle be if a farmer only wanted a cattle with white fur • 3. A cross between a black cat & a tan cat produces a tabby pattern (black and tan fur together)? • A) What pattern of inheritance is this? • B) What percent of kittens would have tan fur if a tabby cat is crossed with a black cat?

  20. THREE ALLELES

  21. MULTIPLE ALLELES • More than three alleles • Many genes have multiple alleles • Three or more different alleles • Exclude dominant and recessive effects • All alleles show its own effects in inheritance • Examples: Blood type, hair color

  22. Multiple alleles cont’d • Multiple alleles - gene has several allelic forms • Example: blood type is determined by multiple alleles • IA= A antigen on red blood cells • IB= B antigen on red blood cells • i= Neither A nor B antigen on red blood cells • Possible phenotypes and genotypes for blood type: • This is an example of codominancebecause both IAand IBare fully expressed

  23. Several genes and the environment can influence a single multifactorial characteristic • Polygenic inheritance occurs when a trait is governed by two or more genes • Multifactorial traits - controlled by polygenes subject to environmental influences

  24. Polygenic inheritance: Dark dots stand for dominant alleles; the shading stands for environmental influences

  25. Iris color

  26. The Human Blood

  27. Skin color

  28. An interesting example is coat color in rabbits • Four different alleles • C (full coat color) • cch (chinchilla pattern of coat color) • Partial defect in pigmentation • ch(himalayan pattern of coat color) • Pigmentation in only certain parts of the body • c (albino) • Lack of pigmentation • The dominance hierarchy is as follows: • C > cch > ch > c • Figure 4 illustrates the relationship between phenotype and genotype

  29. Phenotype Genotype • Agouti (wild type) c+c+, c+cch, c+ch, c+c • Chinchilla (mutant) cchcch • Himalayan(mutant) chch,chc • Light grey cchch, cchc • Albino (mutant) cc FIGURE 4

  30. Why is that? • Caused by tyrosinase; producing melanin • Two types of melanin: eumelanin (black pigment) and phaeomelanin (orange/yellow pigment)

  31. The himalayan pattern of coat color is an example of a temperature-sensitive conditional allele • The enzyme encoded by this gene is functional only at low temperatures • Therefore, dark fur will only occur in cooler areas of the body • This is also the case in the Siamese pattern of coat color in cats

More Related