Role of Hsp90 in FGF-1 and FGF-2 Translocation Process

Jul 05, 2025

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This study uncovers the necessity of cytosolic chaperone Hsp90 for the translocation of FGF-1 and FGF-2 into the cytosol and nucleus. The research sheds light on the molecular mechanisms behind this crucial cellular process.

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Role of Hsp90 in FGF-1 and FGF-2 Translocation Process

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JBC FGF-1 and FGF-2 require the cytosolic chaperone Hsp90 for translocation into the cytosol and the cell nucleus. Wesche J, Malecki J, Wiedlocha A, Skjerpen CS, Claus P, Olsnes S.