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modulation of connectivity. system state. input parameters. state changes. effective connectivity. General bilinear state equation. external inputs. A. B. y 1. y 3. y 2. x 1. x 2. x 3. photic. V1. V5. SPC. u 1. attention. motion. u 3. u 2. Figure 1. neuronal input.
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modulation of connectivity systemstate input parameters state changes effective connectivity General bilinear state equation externalinputs A B y1 y3 y2 x1 x2 x3 photic V1 V5 SPC u1 attention motion u3 u2 Figure 1
neuronal input state variables hemodynamic response Figure 2
A B Attention Photic .52 (98%) .37 (90%) SPC .42 (100%) .56 (99%) .69 (100%) .47 (100%) V1 IFG .82 (100%) Motion V5 .65 (100%) Figure 3
Task factor Task 2 Task 1 T1/S1 T1/S1 Stim 1 Stimulus factor Stim 2 T1/S2 T1/S2 A B y1 Stim 1Task 2 Stim 2Task 2 Stim 2Task 1 Stim 1Task 1 y2 Figure 4
y1 y2 C D – – +++ Stimulus S1 + x2 x1 +++ Stimulus S2 + +++ + Task T1 Task T2 Figure 4 (continued)
mod2 mod1 x3 stim2 x1 x2 stim1 A +++ + – + +++ + + +++ +++ – – Figure 5A
x1 103 y1 x2 103 y2 x3 103 y3 B stim1 stim2 mod1 mod2 mod1 mod2 Figure 5B
inhibitory interneurons 2 3 spiny stellate cells 1 pyramidal cells Intrinsic Forward Backward Lateral Input u Figure 6
inhibitory interneurons spiny stellate cells pyramidal cells Extrinsic lateral connections Extrinsic forward connections Intrinsic connections Extrinsic backward connections Figure 7
standard (predicted) standard (observed) oddball (predicted) oddball (observed) 30 mode 1 PC 20 10 0 -10 OF OF -20 0 200 400 30 mode 2 20 10 2.17 (95%) 2.74 (98%) 3.58 (100%) 4.09 (100%) STG 0 -10 3.23 (97%) -20 0 200 400 A1 A1 30 1.93 (100%) mode 3 20 10 0 -10 input -20 600 0 200 400 0 time (ms) 0 200 400 Figure 8