endonasal removal of invasive gh secreting adenoma acromegaly n.
Download
Skip this Video
Loading SlideShow in 5 Seconds..
Endonasal Removal of Invasive GH-Secreting Adenoma (Acromegaly) PowerPoint Presentation
Download Presentation
Endonasal Removal of Invasive GH-Secreting Adenoma (Acromegaly)

Loading in 2 Seconds...

play fullscreen
1 / 5

Endonasal Removal of Invasive GH-Secreting Adenoma (Acromegaly) - PowerPoint PPT Presentation


  • 85 Views
  • Uploaded on

Endonasal Removal of Invasive GH-Secreting Adenoma (Acromegaly). Acromegaly: Clinical History:. 49 yr man with 10 years of snoring, sleep apnea, coarsened facial features, frontal bossing & prognathism 5 years progressive enlargement of hands & feet 1 year worsening vision

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about 'Endonasal Removal of Invasive GH-Secreting Adenoma (Acromegaly)' - jolie-farley


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
slide2

Acromegaly: Clinical History:

  • 49 yr man with 10 years of snoring, sleep apnea, coarsened facial features, frontal bossing & prognathism
  • 5 years progressive enlargement of hands & feet
  • 1 year worsening vision
  • 6 months hypertension & hypercholesterolemia
  • Hormonal tests: Growth hormone 179 ng/ml (normal < 6); IGF-1 1508 ng/ml, prolactin 184 ng/ml.

1992 1996 2001 2006

acromegaly mri

Acromegaly: MRI

Pre-op MRI shows invasive adenoma with left cavernous sinus and clival invasion. Treated with pre-operative octreotide therapy for 3 weeks then removed by endonasal surgery in near-complete fashion.

slide5

Acromegaly

Post-operative course:

  • Adenoma removed in near-complete fashion.
  • Post-op GH level decreased from 179 to 1 ng/ml; prolactin 2 ng/ml.
  • Patient much improved symptomatically but will need additional therapy (octreotide and/or radiotherapy) for remaining tumor in left cavernous sinus & clivus.