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Explore the microscopic structure of heart, blood vessels, blood cells, connective tissues, cartilage, bone, epithelial, muscular, and nervous tissues in this comprehensive histology program. Includes classifications, functions, and classifications of various tissues.
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Programme of next practicals • April 17th Revision practical + Microscopic structure of the heart and blood vessels. • April 24th Blood cells: Cytology of formed elements of blood. Hematopoiesis– demonstration of developmental stages. Repetition test II (Epithelial tissue, muscle tissue and nervous tissue.) • May 1st, May 8th - Holiday
General histology: Repetition Tissue types • Connective and supporting (+blood) • Epithelial • Muscular • Nervous
Connective tissue developed from mesenchyme consists of: • cells • intercellular matrix: • amorphous ground substance • fibers
Classification • connective tissue proper • specialized connective (supporting) tissue: cartilage bone Functions • mechanical (cartilage, bone) • nutritional (intercellular substance) • defensive (cells: histiocytes, plasma cells, leukocytes – immunocompetence, production of antibodies)
Connective tissue proper • mucous (jelly-like) • loose collagenous (areolar) • dense collagenous (regular, irregular) • reticular • elastic • adipose tissue (white, brown)
Connective tissue proper Mucous (jelly-like) connective tissue
Cartilage composed of cells (chondrocytes) and intercellular matrix: fibers and amorphous substance (chondrocytes present in lacunae within the matrix) fibers: • collagenous only • combination of collagenous and elastic cartilage is nonvascular, without nerves perichondrium – dense irregular connective tissue on the surface: important for growth and nutrition of cartilage Classification according to the kind and amount of fibers: • hyaline cartilage • elastic cartilage • fibrocartilage
Bone • Cells: osteocytes, osteoblasts, osteoclasts, osteoprogenitor cells • Intercellular matrix: collagenous fibers (type I), amorphous substance, inorganic salts • Macroscopically - 2 types: compact (dense) and spongy (cancelous) • Microscopically – 2 types according to the organisation of intercellular substance: woven (nonlamellar) and Haversian (lamellar)
Epithelial tissue Classification on the structural basis (arrangement of cells): • membranes – cells form sheets – the most common type, including most exocrine glands • trabecular – cells are arranged into anastomosing trabeculae – liver, endocrine glands • reticular – stellate cells form a network – thymus Classification on the basis of function : • Covering (lining) epithelia – epithelial membranes • Glandular epithelium • Absorptive epithelium – enterocytes (intestine) • Respiratory epithelium – pneumocytes (lung) • Sensory epithelium – olfactory ep., taste buds • Myoepithelial cells (exocrine glands, m. dilatator pupillae)
Covering epithelia (epithelial membranes) • Simple squamous
Covering epithelia (epithelial membranes) • Simple cuboidal
Covering epithelia (epithelial membranes) • Simple columnar
Covering epithelia (epithelial membranes) • pseudostratified
Covering epithelia (epithelial membranes) • Stratified squamous nonkeratinized
Covering epithelia (epithelial membranes) • Stratified squamous keratinized
Covering epithelia (epithelial membranes) • Stratified columnar
Covering epithelia (epithelial membranes) • transitional
Glandular epithelium Unicellular glands Goblet cells Paneth cells
Glandular epitheliummulticellular glands – ducts and secretory portions (acini, tubules)
Glandular epithelium • Multicellular glands – serous acini and mucous tubules
Muscle tissue Morphological unit of: • Skeletal muscle cell is called muscle fiber – rhabdomyocyte (multinucleated, nuclei at periphery) myofibrils are structures inside the cell, consist of myofilaments (actin, myosin) • Cardiac muscle cell – cardiomyocyte (uninucleated, nucleus centrally) myofibrils, intercallated discs • Smooth muscle cell – leiomyocyte (uninucleated, nucleus centrally) no myofibrils, only myofilaments
Nervous tissue Anatomically: • CNS (central nervous system): brain, spinal cord • PNS (peripheral nervous system): nerves, ganglia Histologically it consists of 2 principal cell types: • nerve cells (neurons) – excitability (irritability) and conductivity • supporting cells (neuroglia)