AOS-HCI Comparing the effects of alligator and horseshoe crab blood on cancer cell viability. Estelle Gong Anu Venkatachalam Ryan Wong Joshua Foo. Background. AOS. HCI. Robust innate immune system of the Singapore horseshoe crab ( Carcinoscorpius rotundicauda )
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Robust innate immune system of the Singapore horseshoe crab (Carcinoscorpiusrotundicauda)
Infection studies on them have demonstrated that a large amount of bacteria was rapidly suppressed.
Proteins found in the blood of horseshoe crabs potentially provides a more effective way of treating cancer
Elucidate specific proteins in Horseshoe crab blood that recognize and bind surface antigens/ PAMPs of cancer cells
To propose potential peptide-based drugs for cancer detection & treatment
Proteins present in horseshoe crab blood recognize and bind PAMPs of cancer cells.
IV: Horseshoe crab blood hemolymph
DV: Proteins that bind PAMPs of cancer cells