ANTIPARKINSONIAN AGENTS. MA. LENY ALDA G. JUSAYAN, MD DEPARTMENT OF PHARMACOLOGY. PARKINSONISM. Tremors are present even at rest Rigidity & impairment of voluntary movements Postural tremor, intention tremors. The UK Parkinson's Disease Society Brain Bank Criteria For Clinical Diagnosis:.
MA. LENY ALDA G. JUSAYAN, MD
DEPARTMENT OF PHARMACOLOGY
begins in the primary motor cortex
descends through the corticospinal and corticobulbar tracts
affects the lower motor neurones in the brain stem and spinal cord.
The main Pathological feature of Parkinson’s disease is the loss of the dopaminergic nigrostriatal pathway
- 3 mg daily
- 0.05 mg starter dose
The net result of all of these medications is the balancing out of the acetylcholine/dopamine balance and an improvement in movement