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30. 25. 20. 15. 10. 5. 0. Pt#3. Pt#5. Pt#8. Pt#13. VEGF-C. Neuropilin 2. VEGF-D. CXCL6. JAG-1. Leptin. IL-6. Fold change (IL-12 treated/medium). 80. 400. 60. 300. 40. 200. 20. 100. 0. 0. Supplemental Figure 1. B. A. medium. hrIL-12. number of vessels. C. D.

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  1. 30 25 20 15 10 5 0 Pt#3 Pt#5 Pt#8 Pt#13 VEGF-C Neuropilin 2 VEGF-D CXCL6 JAG-1 Leptin IL-6 Fold change (IL-12 treated/medium) 80 400 60 300 40 200 20 100 0 0 Supplemental Figure 1 B A medium hrIL-12 number of vessels C D p = 0.02 MRFI aoptotic cells * % ki67 positive cells med IL-12 med IL-12

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