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LKB1/STK11: Insights into its Function and Role in Cancer

LKB1, also known as STK11, is a serine/threonine kinase that plays a crucial role in regulating cellular energy metabolism and growth. Mutations in the LKB1/STK11 gene are associated with Peutz-Jeghers syndrome and contribute to various cancers, making it a critical focus of research in oncology. This overview discusses the molecular mechanisms of LKB1, its signaling pathways, and the implications of its dysregulation in tumorigenesis. Understanding LKB1/STK11 is essential for developing targeted therapies for cancer treatment.

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LKB1/STK11: Insights into its Function and Role in Cancer

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