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Comparative Genome Analysis: Utilizing Complete Genomes for Functional Prediction and Pathway Detection

This study explores the added value of complete genomes in comparative genome analysis. It emphasizes large-scale pattern detection, particularly through function and orthology prediction using bi-directional best hit approaches. By investigating gene presence, absence, and variation, we aim to uncover significant pathways and predict new biological pathways. Our findings illustrate the importance of comprehensive genomic data in enhancing our understanding of genetic functions and evolutionary relationships.

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Comparative Genome Analysis: Utilizing Complete Genomes for Functional Prediction and Pathway Detection

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    1. Day 5: Comparative genome analysis Added value of complete genomes: More sequences Large scale pattern detection in genomes -Function/orthology prediction by bi-directional best hit approaches More than bags of genes (?): -Presence/absence/variation of pathways -Prediction of new pathways

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