Part I: Biomedical Ontologies: A Critical Survey. Barry Smith http://ontology.buffalo.edu/smith. I: Biomedical Ontologies: A Critical Survey
Both UMLS- and OWL-type responses involve ad hoc creation of new terminologies by each separate community, and an open-door policy for admission Many of these terminologies remain as torsos, gather dust, poison the wells, ...
The Good, the Bad, and the UGLY
Species =def Genus + Differentiae
neuron cell differentiation =def
differentiation by which a cell acquires features of a neuron
retinal_cone_cellOntology alignmentOne of the current goals of GO is to align:
def: "A bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone." [MESH:A.11.329.629]
relationship: develops_from CL:0000008
relationship: develops_from CL:0000375Alignment of the two ontologies will permit the generation of consistent and complete definitions
Osteoblast differentiation: Processes whereby an osteoprogenitor cell or a cranial neural crest cell acquires the specialized features of an osteoblast, a bone-forming cell which secretes extracellular matrix.
To build a high quality shared ontology requires hard work and staying powerYou cannot cheat by borrowing from UMLSUMLS (= the UMLS Metathesaurus) is not an ontology