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The Association between Waist Circumference and Renal Insufficiency among Hypertensive Patients. Mrs. Watcharasa Pitug ID. 567110011-2. Contents. Background/Rationale Objective Methods Results Discussion &Conclusions. Background/Rationale.
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Mrs. Watcharasa Pitug
Chronic kidney disease (CKD) has become a global public health problem and is a common condition in the United States
(Alejandro et al.,2009 ; Essam et al.,2008 ; Adam et al., 2007)
In 2004, there were approximately 472,000 patients with treated ESRD (Alejandro et al.,2009 )
By 2030, expected to increase to more than 2 million. The estimated prevalence of earlier CKD stages (stages 1 through 4) in US adults was 24 to 28 million based on the 2000
(Adam et al., 2007)
Relative risk of death in relation to kidney function
CKD -KDOQI classification
Go AS et., 2004
In 2007 : Chronic Renal Insufficiency patients 13.2% in state 3 and 0.61% in state 4
In 2008 : Chronic Renal Insufficiency patients in Thailand 17.5% (สมาคมโรคไตแห่งประเทศไทย, 2008)
Loss of erythropoietin –anaemia
Parathyroid gland disturbances –renal bone disease
Myocardial fibrosis and cardiomyopathy
Active vitamin D
..and many others
No diuresis –overhydration
Correlation between waist circumference and (A) visceral and (B) subcutaneous fat areas assessed by using computed tomography in 75 men (open circle; dotted lines) and 47 women (filled triangle; solid lines) with prevalent chronic kidney disease.
Fabiana et al.,2008
In summary, in agreement with the findings in the general population, the present study shows that WC is not associated with Chronic Renal Insufficiency in individuals. In previous study, associations found between WC and some CVD risk factors were similar to those observed for visceral fat, suggesting that WC is a simple and economic tool to be used more often in epidemiological research also involving patients with CKD. Prospective studies are necessary to evaluate the reproducibility of WC and the ability of this method to predict outcomes in patients with CKD.