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Introduction to Microbiology

Discover the intricacies of Horizontal Gene Transfer (HGT) in microbiology, focusing on conjugation, plasmids, bacteriophages, and more. Learn about the transfer of antibiotic resistance, DNA cloning, and its importance in microbial genetics. Additional resources for in-depth understanding provided. 8

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Introduction to Microbiology

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  1. Introduction to Microbiology Anas Abu-Humaidan M.D. Ph.D. Lecture 8

  2. Horizontal Gene transfer (HGT)

  3. Gene transfer/ Conjugation

  4. Plasmids • 1-200 kbp of circular dsDNA coding for at least one gene. Plasmids can be a Replicon or epitome. • A mechanism for HGT, many are beneficial, classified according to “conjugativity”, compatibility, function. • Important in transfer of antibiotic resistance and virulence factors.

  5. Plasmids

  6. Plasmids

  7. Gene transfer/ Transduction

  8. Bacteriophages

  9. Gene transfer/ Transformation

  10. Gene transfer/ Transformation

  11. Gene transfer/ Transformation

  12. Gene transfer/ Transposition

  13. Implications of HGT / antibiotic resistance

  14. DNA cloning

  15. Further reading and material: • Murray - Medical Microbiology 8th Edition • Section 4: Bacteriology • Chapter 13: Bacterial metabolisim and genetics • Jawetz, Melnick & Adelberg's Medical Microbiology, 26th edition- Section 1: Fundamentals of Microbiology- • Chapter 7:Microbial genetics • Youtube: • Channel: Judith Leatherman • Video : Bacterial genetics part 1 • Video : Bacterial genetics part 2

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