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Comprehensive Analysis of Hsa_STK33 and Mmu_STK33 Protein Sequences

This document provides an in-depth analysis of the protein sequences Hsa_STK33 and Mmu_STK33, focusing on their structural features, potential phosphorylation sites, and evolutionary significance. With detailed examination of the amino acid sequences, including unique motifs and conservation across species, we highlight the biological functions and relevance of these kinases. This report also includes potential implications in protein interactions and pathways they may influence, providing valuable insights for future research.

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Comprehensive Analysis of Hsa_STK33 and Mmu_STK33 Protein Sequences

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  1. Mmu_Stk33 MADPSLNDNPTACPHCAS-SQAGLLCVCPA-GK-SPVLVVEMSQTSSIGSTEFFASQERKKERNTSRE-SSLKDLSIRTSNVERKP-QAQ |||::|:.::| ||:|:| || ::||||:: .: :|||||||||||||||:| : | |||||:|.:|: :| |||: ||||||||: |.| Hsa_STK33 MADSGLDKKSTKCPDCSSASQKDVLCVCSSKTRVPPVLVVEMSQTSSIGSAESLISLERKKEKNINRDITSRKDLPSRTSNVERKASQQQ WSRSNVTVGKIPHIRMDDGAGIEEFYTFGRILGQGSFGMVFEAIDKETGAKWAIKKVNKEKAGSSAMKLLEREVSILKTVNHQHIIHLEQVFESPQKMYL |:|:| | ||:||||:::||:|||:||||||||:||||:|:||.||||.:||||||||||||||||:|||||||:|||:|:|:||||||||||:|:|||| WGRGNFTEGKVPHIRIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQVFETPKKMYL VMELCEDGELKAVMDQRGHFSENETRLIIQSLASAIAYLHNKDIVHRDLKLENIMVKSSFIDDNNEMNLNIKVTDFGLSVQKHGSRSEGMMQTTCGTPIY |||||||||||.::|::||||||||| ||||||||||||||:|||||||||||||||||:||||||:|||||||||||:|:|: ||||:|:|:||||||| VMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQ-SRSEAMLQATCGTPIY MAPEVINAHDYSQQCDIWSIGVIMFILLCGEPPFLANSEEKLYELIKKGELRFENPVWESVSDSAKNTLKQLMKVDPAHRITAKELLDNQWLTGNTLSSA ||||||:|||||||||||||||:|::|| |||||||:|||||:|||:||||:|||:||:|:||.||:.|||||||||||||||||||||||||||.|||. MAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSV RPTNVLEMMKEWKNNPESDEETNTDE----ETEQ--------SAV----YSPSANTAKQPTNAAKK-PAA--ESVGMTSSNSSSSKLLSAESKAEPEKSS |||||||||||||||||| ||..|:| .||: :. |::..:..||:|. .|: ||: :: :| ||: :|||||:|| |:| ||:: RPTNVLEMMKEWKNNPESVEENTTEEKNKPSTEEKLKSYQPWGNVPDANYTSDEEEEKQSTAYEKQFPATSKDNFDMCSSSFTSSKLLPAEIKGEMEKTP ETVGHASVAKTTLKSTTLFRGKKRL 419aa Q924X7 NetPhosScore | ::::.:| . ||.:| |.||:| > 0.7 VTPSQGTATKYPAKSGALSRTKKKL 514aa Q9BYT3 > 0.9 | | | | | | | | | | 10 20 30 40 50 60 70 80 90 100 A C B D E

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