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Outcome : The student will know : -The definition of anemia .

Course title : Hematology (1) Course code :MLHE-201 Supervisor : Prof Dr. Magda Sultan 14/11/ 2013 . Outcome : The student will know : -The definition of anemia . -The classification of anemias . -The diagnosis of anemias. Introduction To Anaemias. 2013.

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Outcome : The student will know : -The definition of anemia .

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  1. Course title : Hematology (1) Course code :MLHE-201 Supervisor : Prof Dr. Magda Sultan 14/11/2013. Outcome : The student will know : • -The definition of anemia . • -The classification of anemias. • -The diagnosis of anemias

  2. Introduction ToAnaemias 2013

  3. Definition of anaemia Reduction below normal in the concentration of Hb or RBCs ( according to age and sex )

  4. Adult male: Hb 13.5-17.5 g/dl RBCs 4.5 – 6.00 Adult female : Hb 12.0- 16.0 g/dl RBCs 3.80-5.00

  5. The approach to the diagnosis : 1-Detection of the anaemia ( by accurate measurements of the patient values) 2-Type of the anaemia . 3-Investigations of the cause of anaemia

  6. Laboratory evaluation of anaemia : 1-Study of the blood : • -Complete blood count ( Hb, Ht, RBCs, Red cell indices , WBC and platelets ) • -Examination of stained blood film . • -Reticulocyte count .

  7. 2- Other laboratory tests : -Serum iron ,TIBC, serum ferritin , B12, folate, Coomb's test , osmotic fragility , G6PD ,Hbelectophoresis ,ESR , liver and kidney functions tests , thyroid tests ,bone marrow examination.

  8. Classification of anaemiasMorphologic classification : Blood film + Red cell indices

  9. 1-Microcytic Hypochromicanaemia : MCV reduced and MCH reduced • 2-Normocytic Normochromicanaemia : MCV normal and MCH normal • 3-Macrocytic anaemia : MCV increased

  10. MicrocyticHypochromicanaemia Causes : 1-Iron deficiency anaemia . 2-Thalathemias. 3-Haemoglobinopathies. 4-Chronic disorders .

  11. Investigations : 1-Serum iron . 2-TIBC . 3-Serum ferritin . 4-Haemoglobin electrophoresis .

  12. NomocyticNormochromicanaemia Causes : 1-Haemolytic anaemia . 2-Post haemorrhagicanaemia . 3-Liver disease . 4- Renal disease . 5-Endocrine disorders . 6-Hypoplastic anaemia . 7-Bone marrow infiltration .

  13. Investigations : 1-Reticulocyte count . 2-Coomb's test . 3-Hb electrophoresis . 4-Osmotic fragility . 5-G6PD 6- Endocrine tests 7-Liver and renal function tests. 8-Bone marrow aspiration and biopsy

  14. Macrocyticanaemia Types : • 1-Megaloblastic 2- Non Megaloblastic Causes : 1-Vitamin B12 deficiency . 2-Folate deficiency . 3-Haemolytic anaemia . 4-Haemorrhage . 5-Alcohol . 6-Liver and thyroid diseases. 7-Hypoplastic bone marrow.

  15. Investigations : 1-Serum B12 2-Folate assay 3-Bone marrow examination 4-Reticulocyte count 5-Tests for liver and thyroid disorders .

  16. Assignement : Student name : Title : Microcytichypochromicanaemia . Student name : Title:Normocyticnormochromicanaemia

  17. Assignment

  18. Training Questions : -Define anaemia . -Mention the morphologic classifications of anaemias. • Reference book : -Essential haematology -Dacie

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