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Do Physicians Find Our AST Reports As Confusing As We Do?. Louis B. Rice, M.D. Louis Stokes Cleveland VA Medical Center and Case Western Reserve University Cleveland, Ohio. Purpose of Study.
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Louis B. Rice, M.D.
Louis Stokes Cleveland VA Medical Center and Case Western Reserve University
A Minimal Inhibitory Concentration (MIC) is defined as:
A. The minimal concentration of an antibiotic required to kill the test organism
B. The minimal concentration of an antibiotic required to prevent growth of a standard inoculum of test organisms
C. The minimal concentration of an antibiotic achievable in human serum
D. The minimal concentration of an antibiotic achievable in human urine
What is a breakpoint?
A. The concentration of an antibiotic required to inhibit growth of an organism in vitro
B. The concentration of an antibiotic that becomes toxic to human tissues
C. The MIC determined to represent a high likelihood for successful treatment of a bacterial strain with a specific antibiotic
Is the Klebsiella oxytoca susceptible to meropenem?
What is the breakpoint for Pseudomonas aeruginosa resistance to ceftazidime?
C. Insufficient information
Under what circumstances would the results of the enterococcal synergy testing shown in this report be useful?
A. For the treatment of urinary tract infection
B. For the treatment of infections in which Gram negative bacilli are also involved
C. For the treatment of endocarditis
D. Synergy testing is never useful
Is the Pantoea strain described above susceptible to cefotetan?
The above culture was taken one week after the culture shown earlier. Is it likely that the Enterobacter isolates represent the same strain from two different cultures?
A. Yes, because both are susceptible to cefepime.
B. No, because their susceptibilities to piperacillin-tazobactam and ceftazidime differ.
C. They could be the same or different. You cannot tell without performing more detailed genetic studies.
What is the breakpoint for cefotetan resistance for the Enterobacter cloacae?