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Psychology 304: Brain and Behaviour Lecture 23

Psychology 304: Brain and Behaviour Lecture 23. Announcement. The grades for the first midterm exam are now available on the course website. The mean score on the midterm exam was 67% (SD = 17%, range = 23% – 97%).

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Psychology 304: Brain and Behaviour Lecture 23

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  1. Psychology 304: Brain and BehaviourLecture 23

  2. Announcement The grades for the first midterm exam are now available on the course website. The mean score on the midterm exam was 67% (SD = 17%, range = 23% – 97%). The TA, Patrick, will be available during his office hours or by appointment for interested students to review their exams: Mondays, 10:00-11:00, Kenny 3506, ppiantad@psych.ubc.ca. 2

  3. Neurodevelopmental Disorders 1. What neurodevelopmental disorders have been identified? (continued)

  4. By the end of today’s class, you should be able to: 1. describe the causes and symptoms of disorders associated with neurodevelopmental abnormalities.

  5. What neurodevelopmental disorders have been identified? (continued) 4. Fetal alcohol syndrome • Occurs when the fetus is exposed to alcohol, resulting in nervous system damage. Caused by neurotoxin exposure and nutrient deficiencies.

  6. Associated with abnormal brain development: smaller frontal lobes, poor production of cell- adhesion molecules, reduced gray matter, neural plasticity and head size, absence of corpus callosum. • Accompanied by mental retardation, altered facial features, stunted growth, and cognitive/behavioural deficits.

  7. Fetal Alcohol Syndrome: Brain Damage

  8. Fetal Alcohol Syndrome: Physical Characteristics

  9. Fetal Alcohol Syndrome: Physical Characteristics

  10. See YouTube video clip on fetal alcohol syndrome: http://www.youtube.com/watch?v=X9ap3Iimimk (15 minutes).

  11. 5. Autism • Occurs as a result of a neurodevelopmental error between 20 and 24 days after conception. Precise error is unknown. • Caused by abnormalities in the gene Hoxa 1 in some, but not all, cases and/or exposure to neurotoxins.

  12. Associated with abnormal brain development: shortened brain stem, underdeveloped and missing nuclei within the brain stem, abnormal frontal lobes, reduced mirror neuron activity, smaller corpus callosum and amygdala.

  13. Accompanied by three core symptoms: 1. reduced capacity for social interaction. 2. reduced capacity for communication. 3. preoccupation with a single subject or activity.Typically, perseveration is observed. In some cases, mental retardation and/or savant abilities are observed.

  14. Autism: Mirror Neuron Activity

  15. 6. Williams syndrome • Occurs when a region of genes on chromosome 7 fails to replicate and, therefore, is missing. Caused by errors in cell division. • Among the genes that are missing on chromosome 7 is a gene that controls the production of elastin, a protein that contributes to elasticity in internal organs and tissues. • Associated with abnormal brain development: characteristic patterns of atypical cortical volume.

  16. William Syndrome: Cortical Volume

  17. Accompanied by mental retardation, impaired spatial cognition, hypersociability, abnormalities in internal organs, and altered facial and body features. • Although individuals with Williams syndrome display language deficits, their language skills are remarkable given their relatively low IQ. Often, great musical abilities are observed.

  18. William Syndrome: Physical Characteristics

  19. William Syndrome: Physical Characteristics

  20. See YouTube video clip on William’s syndrome: http://www.youtube.com/watch?v=7pyNe2TBQi8 (5 minutes).

  21. Neurodevelopmental Disorders 1. What neurodevelopmental disorders have been identified? (continued)

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