JRC Institute for Health and Consumer Protection http://ihcp.jrc.ec.europa.eu/ http://www.jrc.ec.europa.eu/

1. JRC Institute for Health and Consumer Protection http://ihcp.jrc.ec.europa.eu/ http://www.jrc.ec.europa.eu/

2. The Mission of the IHCP • Is • to protect the interests and health of the consumer in the framework • of EU legislation on chemicals, food, and consumer products by • providing scientific and technical support including risk- benefit • assessment and analysis of traceability. Science for a healthier life

3. IHCP Management Team IHCP Director: Elke Anklam Management Support Unit Ray Crandon Validation of Biomedical Testing Methods Laura Gribaldo (Acting) Toxicology and Chemical Substances Ana Paya Perez (Acting) Biotechnology and GMOs Guy Van den Eede Nanotechnology and Molecular Imaging Hermann Stamm Physical & Chemical Exposure Dimitrios Kotzias

4. IHCP Staff and Gender Balance • IHCP Staff (2007) • M • F • Total • Officials • 91 • 56 • 147 • Temporary Agents • 9 • 20 • 29 • Contractual/Auxiliary Agents including the 20 temporary EChA Trainees • 55 • 75 • 130 • Post-Doc Grant-holders/(Trainees) • 1(4) • 1 (5) • 11 • Seconded National Experts • 7 • 2 • 9 • Total IHCP • 167 • 159 • 326

5. Age Distribution of Staff

6. Competences • Life Sciences • Biology/Molecular Biology • Biometrics • Chemistry/Food Chemistry/Biochemistry • Medicine/Nutrition • Pharmacology • Toxicology • Physical Sciences • Biophysics • Engineering • Information Technology • Materials Science • Physics

7. IHCP Support in the Policy Cycle POLICY ANTICIPATION Agenda-setting Identification of Emerging Issues POLICY EVALUATION POLICY FORMULATION Effectiveness & impact assessment (A posteriori impact assessment) Expert Advice e.g. A priori impact assessement 10% 0% 5% IHCP 5% POLICY ADOPTION Decision making process Selection of Policy Options Draft legislation AD-HOC POLICY SUPPORT 5% Crisis-response 75% Validation, Standardisation Certification, benchmarking, monitoring, checking compliance POLICY IMPLEMENTATION

8. IHCP Policy Areas Main topics • Alternative Methods • Chemicals and Biocides • Consumer Products Safety • Environment and Health • Food Safety • GMOs • Nanotechnology Minor topics • Agricultural Products • Antifraud • Illicit Drugs Future topics • Cosmetics • Nutrition and Health • Chinese Medicine Commission Customer DGs • ENV (40%) • SANCO (35%) • ENTR (15%) • AGRI ( 5%) • OLAF • TAXUD • TRADE ( 5%) • JLS }

9. Risk Assessment (mainly on Chemicals) • Classification and Labelling • Support to European Agency on Chemicals (Helsinki, started in July 2007) • Evaluation and validation of alternative testing • Computational models • In-vitro testing methods (3 R methods) • Indoor and Outdoor Exposure

10. Methods • Validation of alternative test methods (in-vitro) • Method validation for GMOs, food contact materials, textiles, food authenticity control • Sampling protocols • Traceability

11. Databases/Repositories • Databases on e.g. alternative methods, IUCLID 5, European wines • Material banks (food contact materials, wine, nanomaterials)

12. Provision of robust analytical data • Analysis in support to implementation of legislation • (complementary to work carried out in IRMM) • Genetically modified organisms • Food contact materials • European wine • Chemicals from consumer products

13. Innovative Tools • Pre-spotted 96 well plates for real-time PCR • Development of biosensors • High-throughput systems

14. Community Reference Laboratories • Community Reference Laboratory for GMOs in Food and Feed • Community Reference Laboratory for Food Contact Materials Complementary to work carried out in JRC-IRMM (Geel): 4 CRLs Complementary to work carried out in EFSA (Parma)

15. EC Customer DGs AGRI: EU wine data base; authenticity assessment of specific agricultural products ENTR: Nanotechnology; alternative methods to replace animal testing for cosmetics and pharmaceuticals; REACH implementation projects; analysis of textiles ENV GMO detection methods; alternative methods for chemicals; risk assessment of chemicals and biocides; databases on chemicals; support to REACH implementation projects; analyses for chemical exposure assessment; evaluation of health effects due to noise and chemicals; manufactured nanomaterials JLS: Illicit drug profiling SANCO: Community Reference Laboratory (CRL) on GMOs in food and feed, CRL on food contact material; exposure and risk for assessment of consumer products; toxicity of nanoparticles; tobacco ingredients OLAF, TAXUD, TRADE: Identification; taxation and monitoring of traded substances (food and chemicals); consolidated antifraud techniques; tracking of GMOs in food and feed

16. IHCP and European Agencies -1 • European Food Safety Authority (EFSA) • Method validation for GMO analysis • Contributing to EFSA's safety assessments on GMOs, food contact materials, pesticides • Working group on nanotechnology • European Environment Agency (EEA) • Participation in Annual Work Plan (with IES), under thematic area Integrated Assessments and Supporting Sustainable Development • Discussion to start up Human Exposure Data Centre

17. IHCP and European Agencies -2 • European Chemicals Agency (ECHA) • Support to start-up of ECHA – it trained the first intake of recruits and also seconded senior staff in the start-up phase • Transfer of REACH-related activities to ECHA. IHCP will continue to support the Agency but ECB officially closed in 2008 • European Medicines Agency (EMEA) • 2002 – IHCP activities concerning the support in the access to information on medicinal products were transferred to EMEA

18. IHCP and its Collaboration Networks • International Organisations: OECD, WHO, CEN, ISO • Member States Authorities: GMOs, REACH, …. • European Network of GMO laboratories • ECVAM’s Scientific Advisory Committee (ESAC) • Various scientific committees (e.g., SCENIHR, SCHER, EPAA) • Indirect Action networks (NoEs)

19. Peer-reviewed IHCP publications: 2003 – 2007

20. Thank you Web: ihcp.jrc.ec.europa.eu Contact: jrc-info-ihcp@ec.europa.eu