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DEGRADASI ASAM AMINO - PowerPoint PPT Presentation


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DEGRADASI ASAM AMINO. Oleh : Henzo Bernando (10507011) Rini Hapsari (10507037) Aldi Pradana (10507091) Wibawa Hendra S (10507053) Dinda Husna (10507057) Kimia ITB 2010. AGENDA. Asparagin Aspartat Valine Methionin Threonin Glutamat Glutamin Histidin Prolin Arginin.

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degradasi asam amino
DEGRADASI ASAM AMINO

Oleh :

HenzoBernando (10507011)

RiniHapsari (10507037)

AldiPradana(10507091)

WibawaHendraS (10507053)

DindaHusna (10507057)

Kimia ITB 2010

agenda
AGENDA
  • Asparagin
  • Aspartat
  • Valine
  • Methionin
  • Threonin
  • Glutamat
  • Glutamin
  • Histidin
  • Prolin
  • Arginin
degradasi asam amino1
DEGRADASI ASAM AMINO
    • Adalahbentukzatantarametabolikutama yang dapatdiubahmenjadiglukosaataudapatdioksidasipadadaurasamsitrat
    • Tiapasam amino memilikijalurdegradasi yang berbeda.
  • Tahappertamayaitupelepasangugusamina
  • Kerangkakarbon 20 asam amino pembentuk protein disalurkanmenjadi 7 molekul : piruvat, asetilKoA, asetoasetilKoA, α-ketoglutarat, suksinilKoA, fumaratdanoksaloasetat
    • Asam amino yang dipecahmenjadiasetil-KoAatauasetoasetil-KoAdisebutketogenik
    • Asam amino yang dipecahmenjadipiruvat, α-ketoglutaratdansuksinilKoA, fumaratatauoksaloasetatdisebutglukogenik
defek glutamat dan glutamin
DefekGlutamatdanGlutamin
  • efeknegatifterhadapintegritasfungsionaldariusus
  • menyebabkanimmunosupresi
  • Mengganggufungsiotak
  • psychiatric disorders
proline degradation dan defect
Proline Degradation dan Defect

Proline transport defect menyebabkanMutant Phenotypes in Homozygote