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Sliding Filament Theory Review. Acetylcholine Actin ATP Ca + ions Myosin heads. Na+/K+ ions Troponin Tropomyosin Sarcoplasmic reticulum Z-line. The “Actors”. Binds to sarcolemma Opens Na+/K+ gated ion channels. Acetylcholine. Pulled by myosin Attaches to Z-line. Actin.

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Presentation Transcript
the actors

Acetylcholine

  • Actin
  • ATP
  • Ca+ ions
  • Myosin heads
  • Na+/K+ ions
  • Troponin
  • Tropomyosin
  • Sarcoplasmic reticulum
  • Z-line
The “Actors”
acetylcholine

Binds to sarcolemma

  • Opens Na+/K+ gated ion channels
Acetylcholine
actin

Pulled by myosin

  • Attaches to Z-line
Actin
slide5

Energizes the power stroke of myosin head

  • Disconnects the myosin cross bridge from the binding site on actin.
  • Fuels the pump that actively transports calcium ions back into the sarcoplasmic reticulum.
ATP
ca ions

Bind to troponin

  • Help expose binding sites on actin
Ca+ ions
na k ions

Depolarize muscle cell

  • Cause Ca+ ions to leave sarcoplasmic reticulum
Na+/K+ Ions
troponin

Binds to tropomyosin

  • When Ca+ present, helps slide tropomyosin off binding sites
Troponin
sarcoplasmic reticulum

Storage of Ca+ ions

  • Released during depolarization
Sarcoplasmic Reticulum
z lines

Pulled together during contraction

  • Attached to actin myofilaments
Z-lines
write a script for the actors

Acetylcholine

  • Actin
  • ATP
  • Ca+ ions
  • Myosin heads
  • Na + /K +ions
  • Troponin
  • Tropomyosin
  • Sarcoplasmic reticulum
  • Z-line
Write a script for the “Actors”