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Lentivirus is a type of retrovirus that is capable of infecting a wide range of cell types, including non-dividing cells. This property makes it a useful tool for gene transfer and gene therapy applications.<br>Lentivirus manufacturing involves the production of lentiviral vectors, which are modified versions of the lentivirus that are used to deliver a specific gene of interest into a target cell.
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Lentivirus Manufacturing Services One-Stop Solution from GenScriptproBio
Lentivirus is a type of retrovirus that is capable of infecting a wide range of cell types, including non-dividing cells. This property makes it a useful tool for gene transfer and gene therapy applications. Lentivirus manufacturing involves the production of lentiviral vectors, which are modified versions of the lentivirus that are used to deliver a specific gene of interest into a target cell.
Lentivirus manufacturing requires specialized equipment and expertise, and is typically performed in a cleanroom environment to minimize the risk of contamination. There are several advantages to using lentivirus as a vector for gene transfer and gene therapy applications:
1. Wide range of host cells: • Lentivirus can infect a wide range of cell types, including non-dividing cells, making it useful for gene transfer applications in a variety of tissues and cell types.
2. High efficiency of gene transfer: • Lentivirus has a high efficiency of gene transfer, with the ability to transduce up to 90% of target cells in some cases.
3. Long-term Expression of Transgenes: • Lentivirus is capable of integrating its genome into the host cell genome, allowing for long-term expression of transgenes.
4. Safety: • Lentiviral vectors have a lower risk of insertional mutagenesis compared to other types of viral vectors, making them a safer option for gene therapy applications.
5. Customization: • Lentiviral vectors can be easily customized to express a specific gene of interest, allowing for the delivery of a wide range of transgenes.
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