1 / 3

Research Insights from Reeves Lab: Bacterial Pathogenesis and Evolution Studies

The Reeves Lab, led by Peter Reeves, Gordon Stevenson, Yaoqin Hong, and Vincent Morales, focuses on understanding bacterial pathogenesis and evolution. Key research areas include the evolutionary relationships of pathogens, such as Shigella—clones of E. coli with multiple origins—and the dynamics between Vibrio cholera pandemic and endemic strains. The lab explores the genetic and functional aspects of bacterial cell surface polysaccharides, including capsules and O-antigens. Utilizing traditional molecular biology techniques, including cloning and bioinformatics, the lab aims to uncover the intricacies of bacterial surface structures.

gary
Download Presentation

Research Insights from Reeves Lab: Bacterial Pathogenesis and Evolution Studies

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Reeves Lab – Level 5 Peter Reeves Gordon Stevenson Yaoqin Hong Vincent Morales

  2. Research interests of Reeves Lab Bacterial pathogenesis and evolution - Examining evolutionary relationships of pathogens eg. Shigella are clones of E. coli that have multiple unrelated origins Relationships between Vibriocholeraepandemic and endemic strains - Genetic and functional basis for bacterial cell surface polysaccharide eg. Genetics and structures of bacterial capsules, O antigens… Roles of O-antigen synthetic proteins, eg. Wzx, Wzy… Protein specificity associated with surface polysaccharide assebmly

  3. Techniques/Tools that we use Traditional molecular biology tools - cloning - site directed knockout/knock in - 1 D PAGE - Immunoblot Also - Sequencing (sanger, ilumina, 454…) - Radioisotope labeling - bioinformatics - possibly protein related work

More Related