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This study by Gulbahce et al. (2012) explores the intricate relationships between viral infections and host networks, shedding light on how these interactions influence disease pathology. By analyzing various virally implicated diseases, the authors provide insights into the mechanisms by which viruses disrupt host cellular functions. The findings emphasize the importance of understanding viral perturbations for developing targeted therapeutic strategies and improving disease management. This work highlights a systematic view of disease etiology through the lens of viral interactions.
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Table 1. Virally implicated diseases. Gulbahce N, Yan H, Dricot A, Padi M, et al. (2012) Viral Perturbations of Host Networks Reflect Disease Etiology. PLoS Comput Biol 8(6): e1002531. doi:10.1371/journal.pcbi.1002531 http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002531