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Boğaziçi University SCIENCE 102 : Sensory Systems Yrd.Doç.Dr. Burak Güçlü Biomedical Engineering Institute. MECHANICAL SENSES. CHEMICAL SENSES. HEARING. VISION. CORTICAL MAPS. Key concepts: Sensory receptor, sense organ, adequate stimulus A classification of receptors:
Yrd.Doç.Dr. Burak Güçlü
Biomedical Engineering Institute
A classification of receptors:
a) teleceptors: concerned with events at a distance
b) exteroceptors: concerned with external environment near at hand
c) interoceptors: concerned with internal environment
d) proprioceptors: information about the position of the body in space at any instant
Some sensory organs have separate receptor cells and synaptic junctions between receptors and afferent nerves (e.g. Vision, hearing, equilibrium, taste). In others, the receptors are specialized ends of nerve fibers (e.g. most cutaneous sense organs).
A nice example: Pacinian corpuscle
Mostly studied tactile receptor, large size, accessible from the mesentery of carnivores, lamellated capsule, a straight unmyelinated neurite in the middle.
If constant strength stimulus is maintained, sometimes the frequency of action potentials declines over time. Phasic receptors adapt rapidly, tonic receptors slowly.
The action potentials are similar in all nerves. How do we distinguish information from different nerves? How do we determine a strong versus light stimulus?
a) Specific nerves, neurons, and networks
b) Frequency of action potentials
c) Number and type of neurons activated
Scale bar: 0.5 mm(Bolanowski et al., 2000)
(Bell et al., 1994)
Stimulus position, movement, direction.
Object texture and weight.
Body position, movement with respect to objects. Different forces and angles.
Sub-modalities are integrated into a complex percept.
Example: wet object, mental rotation
Trauma, stroke, infection, metabolic (e.g. Diabetic neuropathy), autoimmune (e.g.Guillain-Barré syndrome).
Local lesions: sensory nerves damaged, motor nerves conserved
Result:No information about the body, needs visual input, living in a virtual body...
Mirror drawing: Difficult in normals due to sensory conflict, easy for patients with loss of touch/proprioception
Patients can’t explain what they’re doing !!
Awareness of physical existence by touch and proprioception
Mind-brain fusion (read about modern theories of neurophilosophy: Koch, Churchland et al.)
No special area for mind in the brain (contrast to brain surgeon Wilder Penfield)
No hard evidence for mind-brain duality (contrast to Cartesian philosophy)