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HUMAN DISEASE. http://www.ncbi.nlm.nih.gov/pubmedhealth/s/diseases_and_conditions/a/. MEDICAL BIOTECHNOLOGY. Seeks to Understand human health and disease Use biotechnologies to prevent, diagnose, treat/cure disease and its recurrence. HUMAN DISEASE. Acute Structural such as gallstones

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human disease

HUMAN DISEASE

http://www.ncbi.nlm.nih.gov/pubmedhealth/s/diseases_and_conditions/a/

medical biotechnology
MEDICAL BIOTECHNOLOGY
  • Seeks to
    • Understand human health and disease
    • Use biotechnologies to prevent, diagnose, treat/cure disease and its recurrence
human disease1
HUMAN DISEASE
  • Acute
    • Structural such as gallstones
    • Infectious such as pneumonia
  • Chronic
    • stable (stays the same)
    • Progressive, gets worse and sometimes negatively affects other areas of the body
    • Some do both in different people
human disease2
HUMAN DISEASE
  • Genetic – Down’s syndrome
  • Behavioral – smoking causes lung cancer
human disease classified by impacted organ tissue or cellular system
HUMAN DISEASE: Classified by impacted organ, tissue or cellular system
  • Cardiovascular
  • Pulmonary
  • Renal
  • Gastrointestinal
  • Liver and biliary system
  • Hematologic
  • Metabolic
  • Endocrine
human disease classified by impacted organ tissue or cellular system1
HUMAN DISEASE: Classified by impacted organ, tissue or cellular system
  • Women’s and Men’s health
  • oncologic
  • Bone and bone mineral metabolism
  • Musculoskeletal and connective tissue
  • Neurologic
  • Infectious
  • Aging
  • Substance abuse
slide11

http://www.ivy-rose.co.uk/Revise/AnatomyPhysiology/index.php

http://www.nccpa.net/ExamsContentBPOrgans.aspx

case study hepatitis c virus
CASE STUDY HEPATITIS C VIRUS
  • Infection of the liver leading to inflammation
    • Some(15%) people recover from infection; most become chronic carriers
    • Most infections are asymptomatic for about 20 years
    • Complicated disease process that progresses but not in all patients
    • Immune response and genome (HLA) impact outcome
    • Liver cancer
    • Liver failure

NORMAL

FIBROTIC

CIRRHOTIC

case study down syndrome
CASE STUDY – DOWN SYNDROME
  • Genetic defect – 3 copies of chromosome 21 occurs early in embryo development; = error in cell division
  • Identified prenatally
  • Causes problems with the way the body and brain develop
  • Most common chromosomal defect
case study down syndrome1
CASE STUDY – DOWN SYNDROME
  • Mild to severe in terms of physical appearance as well as mental and social development
  • low muscle tone, small stature, an upward slant to the eyes, and a single deep crease across the center of the palm
case study behavioral
CASE STUDY - BEHAVIORAL
  • Lung cancer because of smoking
  • Liver disease because of alcohol abuse
case study myasthenia gravis
CASE STUDY – MYASTHENIA GRAVIS
  • Acquired autoimmune disorder that lessens transmission across neuromuscular junctions weakening muscle responses
    • Autoantibodies to acetylcholine receptor (AChR )block binding of Ach
  • Weakens voluntary skeletal or ocular muscles
  • Loss of facial expression, muscle fatigue, droopy eyelids
  • Female to male ration = 6:4