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Comprehensive Review of Drug Regimens for HIV Treatment: In-Depth Analysis of Recommended Studies

This article presents thorough research on HIV treatment regimens, examining eligible studies and data extraction. It includes cohort studies, regimen dosing, genotypic resistance data, and more.

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Comprehensive Review of Drug Regimens for HIV Treatment: In-Depth Analysis of Recommended Studies

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  1. 8526 citations from all sources using search strategies 8340 citations excluded after preliminary review 186 full-text articles or posters obtained for full review 175 excluded after full review; 28 Cohort studies 23 Non-recommended regimen/dosing 55 Regimen not 2xNRTI + NNRTI/boosted PI 15 Inadequate genotypic resistance data 12 Non-naïve patients 8 Cross sectional studies 10 Review articles 10 Dose-finding/Pharmacokinetic studies 7 Sample size too small (<30 patients) 5 Resistance follow-up period too short/long 1 HBV/HCV coinfectionstudy 1 duplicated report 11 articles describing 10 studies eligible for inclusion and further data extraction

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