Case 4. 2 y/o, Female. Case 4. Case 4. Clinical Impression. RETINOBLASTOMA. What is the differential diagnosis?. p.209 (book) Retrolental fibroplasia Persistence of the primary vitreous Retinal dysplasia Coats’ disease Nematode endophthalmitis.
a congenital developmental anomaly of the eye resulting from failure of the embryological, primary vitreous and hyaloid vasculature to regress, whereby the eye is shorter, develops a cataract, and may present with whitening of the pupil
The scarred vitreous is often stuck to the back of the lens and areas of the retina. This can damage these parts of the eye as well and lead to other eye conditions:
Most children with PHPV in only one eye usually have good vision in the other. These children do not normally complain of reduced vision.