Red Blood Cells (Erythrocytes). Er ythrocytes (RBC). Structure Biconcave disc shape Includes Hemoglobin Lipid s , ATP, carbonic anhydrase Function O 2 and CO 2 transport. Er ythrocytes (RBC). Most abundant type of blood cells 4- 6 million /mm 3 anemi a ; number of RBC below normal
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“Stem cells” have varying potentials:
Red Blood Cells
Myeloid Stem Cell
Lymphoid Stem Cell
A macrophage phagocytizing multiple RBCs
Hereditary defect in RBC metabolism
Manifestations: pallor, jaundice, hemoglobinuria, elevated reticulocyte count
Diagnostics: quantitative assay of G6PD
Normal Red Bone Marrow
► Some athletes try to induce physiological polycythemia?
Why and How?